ChemicalBook--->CAS DataBase List--->132196-54-4

132196-54-4

132196-54-4 Structure

132196-54-4 Structure
IdentificationBack Directory
[Name]

Chrodrimanin B
[CAS]

132196-54-4
[Synonyms]

Chrodrimanin B
[Molecular Formula]

C27H32O8
[MOL File]

132196-54-4.mol
[Molecular Weight]

484.54
Chemical PropertiesBack Directory
[Boiling point ]

663.7±55.0 °C(Predicted)
[density ]

1.35±0.1 g/cm3(Predicted)
[solubility ]

DMSO: Soluble; Ethanol: 1 mg/ml; Methanol: Soluble
[form ]

A solid
[pka]

9.30±0.70(Predicted)
[LogP]

2.968 (est)
Hazard InformationBack Directory
[Description]

Chrodrimanin B is a meroterpenoid fungal metabolite with insecticidal activity against third instar silkworm larvae.
[Uses]

Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity[1].
[Definition]

ChEBI: Chrodrimanin B is an organic heteropentacyclic compound.
[References]

[1] Yan Xu, et al. Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels. PLoS One. 2015 Apr 22;10(4):e0122629. DOI:10.1371/journal.pone.0122629
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