| Identification | Back Directory | [Name]
1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester | [CAS]
132819-92-2 | [Synonyms]
MDK19922
NOD-IN-1
NOD inhibitor 1
NOD-IN-1; COMPOUND 4; MDK19922; MDK 19922; MDK-19922.
1-(toluene-4-sulfonyl)-1H-indole-2-carboxylic acid ethyl ester
1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester | [Molecular Formula]
C18H17NO4S | [MDL Number]
MFCD30496705 | [MOL File]
132819-92-2.mol | [Molecular Weight]
343.4 |
| Chemical Properties | Back Directory | [Melting point ]
98-99 °C | [Boiling point ]
523.3±52.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively. | [IC 50]
NOD1; NOD2 | [References]
[1] Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234. DOI:10.1016/j.bmc.2016.08.044 |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|