Identification | Back Directory | [Name]
TRPC6 inhibitor | [CAS]
1333207-63-8 | [Synonyms]
CPA-1588 TRPC6 inhibitor SAR7334 (hydrochloride) SAR7334 dihydrochloride TRCP6 inhibitor(SAR7334) CPA-1588(dihydrochloride) TRCP6-IN-1 (hydrochloride) TRCP 6 INHIBITOR;SAR 7334;SAR-7334 SAR7334 HYDROCHLORIDE ;TRCP 6 INHIBITOR 4-{[(1R,2R)-2-[(3R)-3-Aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy}-3-chlorobenzonitrile 4-[[(1R,2R)-2-[(3R)-3-Amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile dihydrochloride 4-[[(1R,2R)-2-[(3R)-3-Amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile hydrochloride (1:2) | [Molecular Formula]
C21H24Cl3N3O | [MDL Number]
MFCD27992059 | [MOL File]
1333207-63-8.mol | [Molecular Weight]
440.794 |
Hazard Information | Back Directory | [Uses]
SAR 7334 is a TRCP6 inhibitor with potential for inhibiting pathological cardiac hypertrophy. | [in vivo]
SAR7334 (10?mg/kg, p.o.) suppresses TRPC6-dependent acute HPV in isolated perfused lungs from mice. SAR7334 demonstrates that it is suitable for chronic oral administration. In an initial short-term study, SAR7334 does not change mean arterial pressure in spontaneously hypertensive rats (SHR)[3]. | [storage]
Store at -20°C |
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Company Name: |
SPIRO PHARMA
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Tel: |
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Website: |
www.spiropharma.com.cn |
Company Name: |
Musechem
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Tel: |
+1-800-259-7612 |
Website: |
www.musechem.com |
Company Name: |
Wuhan Topule
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Tel: |
+86-02787215551 +86-19945035818 |
Website: |
http://www.topule.com/ |
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