| Identification | Back Directory | [Name]
ABO (hydrochloride) | [CAS]
2309172-24-3 | [Synonyms]
ABO (hydrochloride)
6-amino-3,4-dihydro-2H-1,4-benzoxazine-3-methanol,dihydrochloride | [Molecular Formula]
C9H14Cl2N2O2 | [MOL File]
2309172-24-3.mol | [Molecular Weight]
253.126 |
| Hazard Information | Back Directory | [Uses]
ABO hydrochloride is a potent modulator of ANXA7 as ABO binds to Thr286 of ANXA7 and inhibits its phosphorylation. ABO promotes autophagy via elevation of ANXA7 and triggering ANXA7 subcellular redistribution[1]. | [References]
[1] Li H, et al. Identification of a small molecule targeting annexin A7. Biochim Biophys Acta. 2013 Sep;1833(9):2092-9. DOI:10.1016/j.bbamcr.2013.04.015 |
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