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2309172-24-3

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2309172-24-3 Structure

2309172-24-3 Structure
IdentificationBack Directory
[Name]

ABO (hydrochloride)
[CAS]

2309172-24-3
[Synonyms]

ABO (hydrochloride)
6-amino-3,4-dihydro-2H-1,4-benzoxazine-3-methanol,dihydrochloride
[Molecular Formula]

C9H14Cl2N2O2
[MOL File]

2309172-24-3.mol
[Molecular Weight]

253.126
Chemical PropertiesBack Directory
[solubility ]

DMF: 2 mg/ml
DMSO: 2 mg/ml
Ethanol: 5 mg/mlPBS (pH 7.2): 5 mg/ml
[form ]

Solid
[color ]

Brown to black
Hazard InformationBack Directory
[Uses]

ABO hydrochloride is a potent modulator of ANXA7 as ABO binds to Thr286 of ANXA7 and inhibits its phosphorylation. ABO promotes autophagy via elevation of ANXA7 and triggering ANXA7 subcellular redistribution[1].
[References]

[1] Li H, et al. Identification of a small molecule targeting annexin A7. Biochim Biophys Acta. 2013 Sep;1833(9):2092-9. DOI:10.1016/j.bbamcr.2013.04.015
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