Identification | Back Directory | [Name]
beta-hydroxyethoxyacetic acid | [CAS]
13382-47-3 | [Synonyms]
beta-hydroxyethoxyacetic acid Acetic acid, (2-hydroxyethoxy)- Acetic acid,2-(2-hydroxyethoxy) Acetic acid,2-(2-hydroxyethoxy) Sodium Salt | [Molecular Formula]
C4H8O4 | [MDL Number]
MFCD11618154 | [MOL File]
13382-47-3.mol | [Molecular Weight]
120.1 |
Hazard Information | Back Directory | [Uses]
(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine[1]. | [in vivo]
The main metabolic pathway of 1,4-Dioxane is oxidized by cytochrome P450 monooxygenase to (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is then rapidly excreted in urine[1]. | [References]
[1] Elisabeth Eckert, et al. Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 15;935:80-4. DOI:10.1016/j.jchromb.2013.07.017 |
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