| Identification | Back Directory | [Name]
AIDS-096149 | [CAS]
134090-73-6 | [Synonyms]
Np-3a
AIDS-096149
H-Gly-Ile-Cys-Ala-Cys-Arg-Arg-Arg-Phe-Cys-Pro-Asn-Ser-Glu-Arg-Phe-Ser-Gly-Tyr-Cys-Arg-Val-Asn-Gly-Ala-Arg-Tyr-Val-Arg-Cys-Cys-Ser-Arg-Arg-OH
CS-I (rabbit), Antiadrenocorticotropin Peptide I (rabbit), Defensin NP 3A (rabbit), Neutrophil Antibiotic Peptide NP-3A (rabbit), Microbicidal Peptide NP-3A (rabbit)
Corticostatin I (rabbit)?/Defensin NP 3A (rabbit), CS-I (rabbit), Neutrophil Antibiotic Peptide NP-3A (rabbit), Microbicidal Peptide NP-3A (rabbit), Antiadrenocorticotropin Peptide I (rabbit)
Corticostatin I (rabbit) trifluoroacetate salt H-Gly-Ile-Cys-Ala-Cys-Arg-Arg-Arg-Phe-Cys-Pro-Asn-Ser-Glu-Arg-Phe-Ser-Gly-Tyr-Cys-Arg-Val-Asn-Gly-Ala-Arg-Tyr-Val-Arg-Cys-Cys-Ser-Arg-Arg-OH trifluoroacetate salt (Disulfide bonds between Cys3 and Cys31/Cys5 and Cys20/Cys10 and Cys30) | [Molecular Formula]
C151H233N53O44S6 | [MOL File]
134090-73-6.mol | [Molecular Weight]
3687.18 |
| Chemical Properties | Back Directory | [Sequence]
Gly-Ile-Cys-Ala-Cys-Arg-Arg-Arg-Phe-Cys-Pro-Asn-Ser-Glu-Arg-Phe-Ser-Gly-Tyr-Cys-Arg-Val-Asn-Gly-Ala-Arg-Tyr-Val-Arg-Cys-Cys-Ser-Arg-Arg (Disulfide bonds between Cys3 and Cys31/Cys? and Cys2?/Cys1? and Cys3?) |
| Hazard Information | Back Directory | [Uses]
Defensin NP-3A (NP-3A; Corticostatin 1) is a human granulocyte peptide, with anti-ACTH activity. Defensins are antimicrobial peptides with and cytotoxic activity[1][2]. | [References]
[1] Singh A, et al. Structure of a novel human granulocyte peptide with anti-ACTH activity. Biochem Biophys Res Commun. 1988 Aug 30;155(1):524-9. DOI:10.1016/s0006-291x(88)81118-5
[2] Lehrer RI, et al. Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol. 1993;11:105-28. DOI:10.1146/annurev.iy.11.040193.000541 |
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