ChemicalBook--->CAS DataBase List--->4237-93-8

4237-93-8

4237-93-8 Structure

4237-93-8 Structure
IdentificationBack Directory
[Name]

ADRENOCORTICOTROPIC HORMONE, FRAGMENT 11-24
[CAS]

4237-93-8
[Synonyms]

(11-24)-ACTH
beta11-24-ACTH
alpha11-24-ACTH
Human ACTH(11-24)
α11-24-Corticotropin
Adrenocorticotropic Hormone (11-24)
Corticotropin-(11-24)-tetradecapeptide
human adrenocorticotropic hormone (11-24)
adrenocorticotropic hormone fragment 11-24, human
ACTH (11-24) H-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
[Molecular Formula]

C77H134N24O16
[MOL File]

4237-93-8.mol
[Molecular Weight]

1652.04
Chemical PropertiesBack Directory
[density ]

1.424±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

Store at -20°C, protect from light, stored under nitrogen
[form ]

Solid
[pka]

3.398±0.20(predicted)
[color ]

White to off-white
[Water Solubility ]

Soluble in Water
[Sequence]

Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Hazard InformationBack Directory
[Uses]

ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist. ACTH (11-24) is a fragment of adrenocorticotropic and induces cortisol release. ACTH (11-24) can be used for the research of central nervous system[1][2].
[in vivo]

ACTH (11-24) has slight influences on circulating plasma corticosterone values and on fighting behavior[2].

[storage]

Store at -20°C, protect from light, stored under nitrogen
[References]

[1] Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6. DOI:10.1210/endo-125-2-592
[2] P F Brain, et al. Acute influences of some ACTH-related peptides of fighting and adrenocortical activity in male laboratory mice. Pharmacol Biochem Behav DOI:10.1016/0091-3057(77)90210-6
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