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1345275-27-5

1345275-27-5 Structure

1345275-27-5 Structure
IdentificationBack Directory
[Name]

(16(17)-DiHDPA
[CAS]

1345275-27-5
[Synonyms]

(16(17)-DiHDPA
(±)16(17)-DiHDPA MaxSpec? Standard
16,17-dihydroxy-4(Z),7(Z),10(Z),13(Z),19(Z)-docosapentaenoic acid
[Molecular Formula]

C22H34O4
[MOL File]

1345275-27-5.mol
[Molecular Weight]

362.5
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.25 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Description]

(±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid (DHA; ). It has been shown to inhibit VEGF-induced angiogenesis and reduce cancer cell metastasis in mice.1
[Definition]

ChEBI: 16,17-DiHDPE is a very long-chain fatty acid.
[References]

1. Zhang, G., Panigrahy, D., Mahakian, L.M., et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis Proc. Natl. Acad. Sci. USA 110(16),6530-6535(2013).
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