| Identification | Back Directory | [Name]
m-PEG6-acid | [CAS]
1347750-72-4 | [Synonyms]
mPEG6-COOH
m-PEG6-acid
mPEG5-propionic acid
4,7,10,13,16,19-Hexaoxaeicosanoic acid
2,5,8,11,14,17-hexaoxaicosan-20-oic acid
2,5,8,11,14,17-Hexaoxa-20-icosanoic Acid
2,5,8,11,14,17-hexaoxaicosan-20-oic acid(WXC06947)
3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid | [Molecular Formula]
C14H28O8 | [MDL Number]
MFCD20926383 | [MOL File]
1347750-72-4.mol | [Molecular Weight]
324.37 |
| Chemical Properties | Back Directory | [Boiling point ]
431.5±45.0 °C(Predicted) | [density ]
1.109±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [solubility ]
Soluble in Water | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
m-PEG6-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG5-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs | [References]
[1] Parva Yogeshchandra Purohit, et al. Prodrugs of fulvestrant. WO2019224790A2. |
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