ChemicalBook--->CAS DataBase List--->1347750-84-8

1347750-84-8

1347750-84-8 Structure

1347750-84-8 Structure
IdentificationBack Directory
[Name]

Maleimide-NH-PEG4-CH2CH2COOPFP Ester
[CAS]

1347750-84-8
[Synonyms]

Mal-NH-PEG4-CH2CH2COOPFP ester
Maleimide-NH-PEG4-CH2CH2COOPFP Ester
(2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
[Molecular Formula]

C24H27F5N2O9
[MDL Number]

MFCD28899322
[MOL File]

1347750-84-8.mol
[Molecular Weight]

582.47
Chemical PropertiesBack Directory
[Boiling point ]

688.9±55.0 °C(Predicted)
[density ]

1.387±0.06 g/cm3(Predicted)
[pka]

15.01±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Mal-NH-PEG4-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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