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1350752-07-6

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1350752-07-6 Structure

1350752-07-6 Structure
IdentificationBack Directory
[Name]

2-chloro-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
[CAS]

1350752-07-6
[Synonyms]

5WKS
2-Chloro-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-am
2-chloro-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
4-Quinazolinamine, 2-chloro-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-
[Molecular Formula]

C24H36ClN5O2
[MDL Number]

MFCD27978465
[MOL File]

1350752-07-6.mol
[Molecular Weight]

462.03
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

G9a-IN-1 (Compound 113) is a G9a protein inhibitor. G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes histone H3 lysine 9 dimethylation (H3K9me2), which is a reversible modification generally associated with transcriptional gene silencing. G9a-IN-1 can be used for the research of autoimmune disorders or cancer[1].
[References]

[1] Dimitrios Iliopoulos, et al. Small molecules for the treatment of autoimmune diseases and cancer. WO2022031939A1
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