| Identification | More | [Name]
2,5-Dichlorophenylboronic acid | [CAS]
135145-90-3 | [Synonyms]
2,5-DICHLOROBENZENEBORONIC ACID
2,5-DICHLOROPHENYLBORONIC ACID
AKOS BRN-0160
RARECHEM AH PB 0097
2,5-Dichlorophenylboronic
2,5-DICHLOROBENZENEBORONIC ACID 98+%
2,5-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
2,5-Dichlorophenylboronic acid ,98% | [Molecular Formula]
C6H5BCl2O2 | [MDL Number]
MFCD01863182 | [Molecular Weight]
190.82 | [MOL File]
135145-90-3.mol |
| Chemical Properties | Back Directory | [Appearance]
White to off-white powder | [Melting point ]
150 °C(lit.) | [Boiling point ]
343.6±52.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
Acetone (Slightly), Methanol (Slightly) | [form ]
Powder | [pka]
7.26±0.58(Predicted) | [color ]
White to off-white | [Detection Methods]
HPLC,NMR | [BRN ]
4801290 | [InChI]
1S/C6H5BCl2O2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H | [InChIKey]
NNTFPBXQPOQRBT-UHFFFAOYSA-N | [SMILES]
OB(O)c1cc(Cl)ccc1Cl | [CAS DataBase Reference]
135145-90-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29163990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
2,5-Dichlorophenylboronic Acid is a reactant in the synthesis of Dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes. | [Uses]
Reactant for:• ;Regioselective iodination using silver salts1• ;Pd-catalyzed Suzuki-Miyaura coupling2• ;Rhodium(I)-catalyzed carbonylative cyclization of alkynes3• ;Copper catalyzed coupling reactions4 | [Uses]
suzuki reaction |
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