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1352546-80-5

1352546-80-5 Structure

1352546-80-5 Structure
IdentificationBack Directory
[Name]

1-(t-Boc-Aminooxy)-3-aminooxy-propane
[CAS]

1352546-80-5
[Synonyms]

BUN 46805
1-(t-Boc-Aminooxy)-3-aminooxy-propane
Carbamic acid, N-[3-(aminooxy)propoxy]-, 1,1-dimethylethyl ester
[Molecular Formula]

C8H18N2O4
[MDL Number]

MFCD28397120
[MOL File]

1352546-80-5.mol
[Molecular Weight]

206.24
Hazard InformationBack Directory
[Description]

1-(t-Boc-Aminooxy)-3-aminooxy-propane is a small PEG reagent containing an aminooxy group and a Boc protected aminoxy group. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
[Uses]

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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