| Identification | Back Directory | [Name]
4-FLUORO-N-(2-[4-(7-METHOXY-NAPHTHALEN-1-YL)-PIPERAZIN-1-YL]-ETHYL)-BENZAMIDE | [CAS]
135722-25-7 | [Synonyms]
S 14506
BENZAMIDE, 4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]-
4-FLUORO-N-(2-[4-(7-METHOXY-NAPHTHALEN-1-YL)-PIPERAZIN-1-YL]-ETHYL)-BENZAMIDE | [Molecular Formula]
C24H26FN3O2 | [MDL Number]
MFCD10565908 | [MOL File]
135722-25-7.mol | [Molecular Weight]
407.48 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble,Ethanol: soluble | [form ]
A solid | [InChI]
InChI=1S/C24H26FN3O2/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19/h2-10,17H,11-16H2,1H3,(H,26,29) | [InChIKey]
IFMQODYDAUKKEN-UHFFFAOYSA-N | [SMILES]
C(NCCN1CCN(C2=C3C(C=CC(OC)=C3)=CC=C2)CC1)(=O)C1=CC=C(F)C=C1 |
| Hazard Information | Back Directory | [Uses]
S 14506 is a full, highly potent and selective SR-1A agonist. | [Definition]
ChEBI:4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide is a benzamide obtained by formal condensation of the carboxy group of 4-fluorobenzoic acid with the primary amino group of 2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethylamine. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo. It has a role as an anxiolytic drug and a serotonergic agonist. It is a N-arylpiperazine, a N-alkylpiperazine, a methoxynaphthalene, a member of benzamides and an organofluorine compound. It is a conjugate base of a 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide(1+). | [storage]
Store at -20°C |
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ChemeGen Gold
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18818260767 |
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https://www.chemegen.com |
| Company Name: |
BOC Sciences
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https://www.bocsci.com |
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