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1357266-80-8

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1357266-80-8 Structure

1357266-80-8 Structure
IdentificationBack Directory
[Name]

(R)-4-(3-FLUORO-2-METHYLPHENYL)-4,5-DIHYDROOXAZOL-2-AMINE
[CAS]

1357266-80-8
[Synonyms]

(4R)-RO5263397
(R)-4-(3-FLUORO-2-METHYLPHENYL)-4,5-DIHYDROOXAZOL-2-AMINE
(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamine
2-Oxazolamine, 4-(3-fluoro-2-methylphenyl)-4,5-dihydro-, (4R)-
[Molecular Formula]

C10H11FN2O
[MDL Number]

MFCD28405324
[MOL File]

1357266-80-8.mol
[Molecular Weight]

194.21
Chemical PropertiesBack Directory
[Boiling point ]

303.9±52.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

7.68±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

(R)-RO5263397 is a TAAR 1 agonist that demonstrates efficacy in reducing cocaine-mediated behaviors, including cocaine-induced behavioral sensitization, cue- and cocaine prime-induced reinstatement of cocaine-seeking behavior, and the expression of conditioned place preference.
[References]

[1] Effects of the trace amine-associated receptor 1 agonist RO5263397 on abuse-related effects of cocaine in rats
Spectrum DetailBack Directory
[Spectrum Detail]

(R)-4-(3-FLUORO-2-METHYLPHENYL)-4,5-DIHYDROOXAZOL-2-AMINE(1357266-80-8)1HNMR
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