| Identification | Back Directory | [Name]
4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, (4Z,7Z,10R,11E,13E,15Z,17R,19Z)- | [CAS]
1365694-03-6 | [Synonyms]
17(R)-Protectin D1
4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, (4Z,7Z,10R,11E,13E,15Z,17R,19Z)- | [Molecular Formula]
C22H32O4 | [MOL File]
1365694-03-6.mol | [Molecular Weight]
360.49 |
| Hazard Information | Back Directory | [Biological Activity]
17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1 It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when used at concentrations ranging from 0.1 to 10 nM. 17(R)-Protectin D1 (0.01-10 ng) reduces the recruitment of neutrophils in a mouse model of TNF-α-induced peritonitis. | [storage]
-80°C | [References]
1.Serhan, C.N., Fredman, G., Yang, R., et al.Novel proresolving aspirin-triggered DHA pathwayChem. Biol.18(18)976-987(2011)
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