| Identification | Back Directory | [Name]
Protein kinase inhibitors 1 | [CAS]
1365986-44-2 | [Synonyms]
HIPK2 inhibitor
Reaxys ID: 21909876
Protein kinase inhibitors 1
A64 trifluoroacetate >=98% (HPLC)
2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]- | [Molecular Formula]
C18H17N5O3S | [MDL Number]
MFCD31619322 | [MOL File]
1365986-44-2.mol | [Molecular Weight]
383.42 |
| Chemical Properties | Back Directory | [density ]
1.487±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
5.58±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | [References]
[1] Miduturu CV, et al. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinaseinhibitors. Chem Biol. 2011 Jul 29;18(7):868-79. DOI:10.1016/j.chembiol.2011.05.010 |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|