| Identification | Back Directory | [Name]
nisin Z | [CAS]
137061-46-2 | [Synonyms]
nisin Z
Nisin A, 27-L-asparagine-
Nisin Z (~80%)
DISCONTINUED. Please see N487558. | [Molecular Formula]
C141H229N41O38S7 | [MOL File]
137061-46-2.mol | [Molecular Weight]
3331.05 |
| Chemical Properties | Back Directory | [Boiling point ]
2962.5±65.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [solubility ]
DMSO (Slightly, Heated), Water (Slightly, Heated, Sonicated) | [form ]
Solid | [color ]
Off-White to Light Beige | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Food preservative, especially. for cheese and other dairy products, canned vegetables, and some baked goods. | [Uses]
Nisin Z is a peptide antibiotic synthesized by Lactococcus lactis. Nisin Z interacts?with lipid II, a lipid component of cell wall, to form pores in the plasma membrane. | [in vivo]
Nisin Z (1, 5, and 10 mg/kg, i.p.) prevents the pathological damage in mastitis mouse mode caused by LPS[4].
| Animal Model: | Mastitis mouse model[4] | | Dosage: | 1, 5, and 10 mg/kg | | Administration: | i.p., one hour before treatment of LPS. | | Result: | Reduced inflammatory cell infiltration.
Showed a reduction in inflammatory cytokine levels.
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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