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139145-27-0

139145-27-0 Structure

139145-27-0 Structure
IdentificationBack Directory
[Name]

4-Bromo-6-[3-(4-chlorophenyl)propoxy]-5-(pyridin-3-ylmethylamino)pyridazin-3(2H)-one hydrochloride (free base)
[CAS]

139145-27-0
[Synonyms]

Parogrelil
Parogrelil - NT 702, free base | NM 702
4-Bromo-6-[3-(4-chlorophenyl)propoxy]-5-[(3-pyridinylmethyl)amino]-3(2H)-pyridazinone
4-bromo-6-(3-(4-chlorophenyl)propoxy)-5-((pyridin-3-ylmethyl)amino)pyridazin-3(2H)-one
3(2H)-Pyridazinone, 4-bromo-6-[3-(4-chlorophenyl)propoxy]-5-[(3-pyridinylmethyl)amino]-
4-Bromo-6-[3-(4-chlorophenyl)propoxy]-5-(pyridin-3-ylmethylamino)pyridazin-3(2H)-one hydrochloride (free base)
[Molecular Formula]

C19H18BrClN4O2
[MOL File]

139145-27-0.mol
[Molecular Weight]

449.73
Chemical PropertiesBack Directory
[density ]

1.51
Hazard InformationBack Directory
[Uses]

Parogrelil (NT-702 free base) is a compound with intermittent claudication inhibitory activity that inhibits PDE3, inhibits platelet aggregation and vasoconstriction, and improves walking distance and plantar surface temperature in a rat experimental model.
[References]

[1] NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental intermittent claudication model DOI:10.1016/j.lfs.2007.07.025
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