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139713-80-7

139713-80-7 Structure

139713-80-7 Structure
IdentificationBack Directory
[Name]

16-Hydroxytriptolide
[CAS]

139713-80-7
[Synonyms]

16-Hydroxytriptolide
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-6a-[(1S)-2-hydroxy-1-methylethyl]-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
[Molecular Formula]

C20H24O7
[MDL Number]

MFCD11045073
[MOL File]

139713-80-7.mol
[Molecular Weight]

376.4
Chemical PropertiesBack Directory
[Melting point ]

232-233.5 °C
[Boiling point ]

659.7±55.0 °C(Predicted)
[density ]

1.56±0.1 g/cm3(Predicted)
[pka]

14.16±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

16-Hydroxytriptolide is a diterpenoid triepoxide naturally isolated from Tripterygium wilfordii plant. This compound showed definite antiinflammatory action, strong immunosuppressive and antifertility activities.
[Definition]

ChEBI: 16-hydroxytriptolide is a tetracyclic diterpenoid with formula C20H24O7, originally isolated from the roots and leaves of Tripterygium wilfordii. It has a role as a plant metabolite, a rat metabolite and a xenobiotic metabolite. It is a gamma-lactone, an epoxide, a secondary alcohol, a tetracyclic diterpenoid, a primary alcohol and a diol.
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