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1401031-52-4

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1401031-52-4 Structure

1401031-52-4 Structure
IdentificationBack Directory
[Name]

N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide
[CAS]

1401031-52-4
[Synonyms]

100859
LSN2463359
N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide
N-(1-Methylethyl)-5-(pridin-4-ylethynyl)pyridine-2-carboxamide
N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide
2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]-
[EINECS(EC#)]

802-759-0
[Molecular Formula]

C16H15N3O
[MDL Number]

MFCD23136020
[MOL File]

1401031-52-4.mol
[Molecular Weight]

265.31
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble10mg/mL, clear
[form ]

powder
[color ]

white to light brown
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

22-36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

LSN 2463359 is used as a positive and potent allosteric modulator of the mGlu5 receptor (1,2). LSN 2463359 is highly selective for mGlu5 and exhibits little to no activity for mGlu1-4, mGlu8 and GABAB receptors. Studies showed that LSN 2463359 promotes wakefulness in vivo and cognitive activity. LSN 2463359 also Improve memory and learning characteristics in mice.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide(1401031-52-4)1HNMR
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