| Identification | Back Directory | [Name]
McMMAD | [CAS]
1401963-15-2 | [Synonyms]
McMMAD
Mc-MMAD
Mc MMAD
MC MMAD; MCMMAD
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide | [Molecular Formula]
C51H77N7O9S | [MDL Number]
MFCD26960951 | [MOL File]
1401963-15-2.mol | [Molecular Weight]
964.26 |
| Chemical Properties | Back Directory | [Boiling point ]
1054.1±65.0 °C(Predicted) | [density ]
1.168±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C,unstable in solution, ready to use. | [solubility ]
DMSO: ≥ 100 mg/mL (103.71 mM); Water: < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
13.63±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC. | [IC 50]
Auristatin | [storage]
Store at -20°C,unstable in solution, ready to use. | [References]
[1] Antibody-drug conjugates Patent: WO 2013068874 A1 |
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|