| Chemical Properties | Back Directory | [Boiling point ]
529.9±50.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 2 mg/ml | [form ]
A crystalline solid | [pka]
13.83±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
BRD4884 is a selective HDAC2 inhibitor. It acts by enhancing the learning and memory processes. | [Uses]
BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3, respectively[1]. | [IC 50]
HDAC1: 29 nM (IC50); HDAC2: 62 nM (IC50); HDAC3: 1.09 μM (IC50) | [References]
[1] Wagner FF, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chem Sci. 2015 Jan 1;6(1):804-815. DOI:10.1039/C4SC02130D |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|