| Chemical Properties | Back Directory | [density ]
1.562±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
7.71±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53. | [Uses]
RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively[1]. | [storage]
Store at -20°C | [References]
[1] Graves B, et al. Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11788-93. DOI:10.1073/pnas.1203789109 |
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| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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