ChemicalBook--->CAS DataBase List--->1416983-77-1

1416983-77-1

1416983-77-1 Structure

1416983-77-1 Structure
IdentificationBack Directory
[Name]

Msg 606
[CAS]

1416983-77-1
[Synonyms]

Msg 606
Glycinamide, N-(4-mercapto-1-oxobutyl)glycyl-L-histidyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-cysteinyl-L-α-aspartyl-L-arginyl-L-phenylalanyl-, cyclic (1→6)-thioether
(3S)-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[(9S,12S,15S)-12-benzyl-9-[3-(diaminomethylideneamino)propyl]-15-(1~{H}-imidazol-5-ylmethyl)-6-(1~{H}-indol-3-ylmethyl)-5,8,11,14,17,20-hexaoxo-1-thia-4,7,10,13,16,19-hexazacyclotricosane-3-carbonyl]amino]-4-oxobutanoic acid
[Molecular Formula]

C62H82N20O13S
[MDL Number]

MFCD30474719
[MOL File]

1416983-77-1.mol
[Molecular Weight]

1347.51
Chemical PropertiesBack Directory
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

4.18±0.10(Predicted)
[color ]

White to off-white
[Water Solubility ]

Soluble to 1 mg/ml in water
Hazard InformationBack Directory
[Uses]

MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects[1].
[storage]

Store at -20°C
[References]

[1] Xu W, et al. Activation of Melanocortin 1 Receptor Attenuates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage viathe Suppression of Neuroinflammation through AMPK/TBK1/NF-κB Pathway in Rats. Neurotherapeutics. 2020;17(1):294-308 DOI:10.1007/s13311-019-00772-x
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