| Identification | Back Directory | [Name]
D-Prolinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysyl-D-valyl-, (2→7)-lactam | [CAS]
1456699-27-6 | [Synonyms]
D-Prolinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysyl-D-valyl-, (2→7)-lactam | [Molecular Formula]
C63H87N15O11 | [MOL File]
1456699-27-6.mol | [Molecular Weight]
1230.46 |
| Chemical Properties | Back Directory | [density ]
1.41±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.14±0.70(Predicted) | [color ]
White to off-white | [Sequence]
Ac-Nle-c[Asp-Pro-D-Nal(2')-Arg-Trp-Lys]-dVal-dPro-NH2 |
| Hazard Information | Back Directory | [Uses]
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia[1]. | [References]
[1] Yongjun Hu, et al. Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1677-1687. DOI:10.1002/jcsm.12602 |
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YantaiBio
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13758194781; 13758194781 |
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Fuan Bio
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15002819872 |
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fuanbio.com |
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