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1417440-37-9

1417440-37-9 Structure

1417440-37-9 Structure
IdentificationBack Directory
[Name]

2,3-Dihydro-3-hydroxy-2-[[2-[(2-naphthalenylmethyl)sulfonyl]acetyl]imino]-4-thiazoleacetic acid
[CAS]

1417440-37-9
[Synonyms]

BNS >=98% (HPLC)
2,3-Dihydro-3-hydroxy-2-[[2-[(2-naphthalenylmethyl)sulfonyl]acetyl]imino]-4-thiazoleacetic acid
[Molecular Formula]

C18H16N2O6S2
[MDL Number]

MFCD30738204
[MOL File]

1417440-37-9.mol
[Molecular Weight]

420.459
Chemical PropertiesBack Directory
[Boiling point ]

773.6±70.0 °C(Predicted)
[density ]

1.52±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

4.58±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

BNS is a potent and selective inhibitor of prolyl-hydroxylase 2 (PHD2).
[Uses]

BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor[1].
[References]

[1] Leung IK, et al. Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors. J Med Chem. 2013 Jan 24;56(2):547-55. DOI:10.1021/jm301583m
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