ChemicalBook--->CAS DataBase List--->1420367-28-7

1420367-28-7

1420367-28-7 Structure

1420367-28-7 Structure
IdentificationBack Directory
[Name]

Lp-PLA2 -IN-1
[CAS]

1420367-28-7
[Synonyms]

Lp-PLA2 -IN-1
Lp-PLA2 inhibitor
Lp-PLA2 inhibitor 1
GSK 2814338;GSK-2814338
Lp-PLA2 -IN-1(GSK2814338)
[Molecular Formula]

C21H17F5N4O3
[MOL File]

1420367-28-7.mol
[Molecular Weight]

468.38
Chemical PropertiesBack Directory
[Boiling point ]

483.5±55.0 °C(Predicted)
[density ]

1.47±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Ethanol:25.0(Max Conc. mg/mL);53.38(Max Conc. mM)
[form ]

Solid
[pka]

3.84±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research[1].
[IC 50]

Lp-PLA2
[storage]

Store at -20°C
[References]

[1] Zehong Wan, et al. Bicyclic pyrimidone compounds. WO2013014185A1.
Spectrum DetailBack Directory
[Spectrum Detail]

Lp-PLA2 -IN-1(1420367-28-7)1HNMR
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