| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-[(4-bromophenyl)thio]- | [CAS]
14204-32-1 | [Synonyms]
hCAI/II-IN-7
1H-Isoindole-1,3(2H)-dione, 2-[(4-bromophenyl)thio]- | [Molecular Formula]
C14H8BrNO2S | [MOL File]
14204-32-1.mol | [Molecular Weight]
334.19 |
| Hazard Information | Back Directory | [Uses]
hCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 23 nM, 44 nM and 20.57?μM for hCA-I, hCA-II and bovine CA, respectively[1]. | [IC 50]
hCA I: 23 nM (Ki); hCA II: 44 nM (Ki); bovine CA: 20.57 μM (Ki) | [References]
[1] Hasan Yakan, et al. Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2194573. DOI:10.1080/14756366.2023.2194573 |
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