ChemicalBook--->CAS DataBase List--->1421923-86-5

1421923-86-5

1421923-86-5 Structure

1421923-86-5 Structure
IdentificationBack Directory
[Name]

KPT-330, (E)-RN
[CAS]

1421923-86-5
[Synonyms]

Kpt-330, (E)-
KPT-330, (E)-RN
Selinexor E-isomer
Selinexor trans-isomer
SELINEXOR;KPT-330; (E)-RN
(E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
(E)-3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-N'-(PYRAZIN-2-YL)ACRYLOHYDRAZIDE
2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2E)-
KPT-330, (E)-RN (E)-3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-N'-(PYRAZIN-2-YL)ACRYLOHYDRAZIDE
[Molecular Formula]

C17H11F6N7O
[MDL Number]

MFCD28559396
[MOL File]

1421923-86-5.mol
[Molecular Weight]

443.31
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[pka]

9.74±0.43(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

KPT-330 is an orally bioavailable selective?Chromosome Region Maintenance (CRM1)?inhibitor, that has been shown to block pancreatic cancer cell proliferation and reduce tumor growth in mice.
Spectrum DetailBack Directory
[Spectrum Detail]

KPT-330, (E)-RN(1421923-86-5)1HNMR
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