| Identification | Back Directory | [Name]
Benzamide, 2-chloro-4-fluoro-3-methyl-N-[2-(4-methyl-1-piperazinyl)-5-nitrophenyl]- | [CAS]
1422389-91-0 | [Synonyms]
WDR5-47
2-Chloro-4-fluoro-3-methyl-N-(2-(4-methylpiperazin-1-yl)-5-nitrophenyl)benzamide
Benzamide, 2-chloro-4-fluoro-3-methyl-N-[2-(4-methyl-1-piperazinyl)-5-nitrophenyl]- | [Molecular Formula]
C19H20ClFN4O3 | [MOL File]
1422389-91-0.mol | [Molecular Weight]
406.84 |
| Hazard Information | Back Directory | [Uses]
WDR5-MLL1 antagonist 1 (compound 47) is a compound optimized through protein crystal structure guidance. It has stronger antagonistic activity against WDR5-MLL interaction with a dissociation constant (Kd) of 0.3μM. | [References]
[1] Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction |
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