| Identification | Back Directory | [Name]
JWH 210 N-pentanoic acid metabolite | [CAS]
1427521-36-5 | [Synonyms]
PKGSQKIUCYVUDF-UHFFFAOYSA-N
JWH 210 N-pentanoic acid metabolite
3-[(4-ethyl-1-naphthalenyl)carbonyl]-1H-indole-1-pentanoicacid | [Molecular Formula]
C26H25NO3 | [MOL File]
1427521-36-5.mol | [Molecular Weight]
399.48 |
| Hazard Information | Back Directory | [Description]
JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with 5-carboxypentyl metabolites detected in the urine.1,2,3 JWH 210 N-pentanoic acid metabolite is an expected metabolite of JWH 210, detectable primarily in the urine. Its biological activities have yet to be determined. | [References]
1. Teske, J., Weller, J.P., Fieguth, A., et al. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27),2659-2663(2010).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010). |
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