ChemicalBook--->CAS DataBase List--->143-74-8

143-74-8

143-74-8 Structure

143-74-8 Structure
IdentificationMore
[Name]

Phenol Red
[CAS]

143-74-8
[Synonyms]

3,3-BIS(P-HYDROXYPHENYL)-2,1-3H-BENZOXATHIOLE
A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE
LABOTEST-BB LT00455865
PHENOL RED
PHENOLSULFONEPHTHALEIN
PHENOLSULFONPHTHALEIN
PHENOLSULFONPHTHALEIN TEST SOLUTION
PHENOLSULPHONEPHTHALEIN
PHENOSULFOHEPHTHALEIN INDICATOR
PHENYLSULFONEPHTHALEIN
PHENYLSULFONPHTHALEIN
PR
SULFONAPHTHAL
TIMTEC-BB SBB006473
3,3-bis(p-Hydroxyphenyl)-3H-2,1-benzoxathiol-1,1-dioxide
4,4’-(3h-2,1-benzoxathiol-3-ylidene)bisphenol,s,s-dioxide
4,4’-(3h-2,1-benzoxathiol-3-ylidene)diphenol,s,s-dioxide
abcolphenolredf/a
fenolipuna
Phenol,4,4’-(3H-2,1-benzoxathiol-3-ylidene)bis-,S,S-dioxide
[EINECS(EC#)]

205-609-7
[Molecular Formula]

C19H14O5S
[MDL Number]

MFCD00003552
[Molecular Weight]

354.38
[MOL File]

143-74-8.mol
Chemical PropertiesBack Directory
[Appearance]

red-brown powder
[Melting point ]

>300 °C
[Boiling point ]

>300°C
[bulk density]

200-300kg/m3
[density ]

1.445 Mg m-3
[refractive index ]

1.5300 (estimate)
[Fp ]

>300°C
[storage temp. ]

Store at RT.
[solubility ]

1 M NaOH: soluble1mg/mL
[form ]

Solid
[pka]

7.9(at 25℃)
[color ]

Red
[Odor]

Odorless
[PH]

6.8~8.4
[PH Range]

6.6(YELLOW)-8.0(RED)
[Water Solubility ]

0.77 g/L
[ε(extinction coefficient)]

≥10000 at 288-294nm in H2O
≥55000 at 555-561nm in H2O
≥7000 at 357-363nm in H2O
[λmax]

557nm, 558nm, 360nm, 423nm, 433nm
[Merck ]

14,7247
[BRN ]

326470
[Major Application]

Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity
[Cosmetics Ingredients Functions]

BUFFERING
[InChI]

1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
[InChIKey]

BELBBZDIHDAJOR-UHFFFAOYSA-N
[LogP]

3.020
[CAS DataBase Reference]

143-74-8(CAS DataBase Reference)
[EPA Substance Registry System]

143-74-8(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340+P312
[Hazard Codes ]

Xi,C
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
[Safety Statements ]

S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
[WGK Germany ]

3
[RTECS ]

SJ7490000
[TSCA ]

Yes
[HS Code ]

29349990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Skin Irrit. 2
STOT SE 3
[Toxicity]

LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Zinc chloride-->2-Sulfobenzoic anhydride-->L-Cysteine hydrochloride monohydrate
[Preparation Products]

Bromophenol Blue
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Phenolsulfonephthalein(143-74-8).msds
Hazard InformationBack Directory
[Description]

Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.
[Chemical Properties]

dark red powder
[Uses]

As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red.
[Application]

Phenol red solution has been used:
As a tracer dye for microinjection of zebrafish eggs.
As a component of the mMW medium for preparation of mouse embryos.
In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution.
[Definition]

ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.
[Preparation]

Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.
[Biochem/physiol Actions]

Phenol Red is a pH indicator which changes color from yellow to red.
[Safety Profile]

Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx.
[Enzyme inhibitor]

This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination.
Spectrum DetailBack Directory
[Spectrum Detail]

Phenol Red(143-74-8)MS
Phenol Red(143-74-8)1HNMR
Phenol Red(143-74-8)13CNMR
Phenol Red(143-74-8)IR1
Phenol Red(143-74-8)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Phenol Red, conform to ACS, pure(143-74-8)
[Alfa Aesar]

Phenol Red, ACS(143-74-8)
[Sigma Aldrich]

143-74-8(sigmaaldrich)
[TCI AMERICA]

Phenol Red(143-74-8)
143-74-8 suppliers list
Company Name: Kaiyuan city Shenxin fine chemical co., ltd.  Gold
Telephone: 024-22595298 18698863499
Website: http://www.shenxinchem.com/
Company Name: Shenyang Xianchuang Chemical Co., Ltd.  Gold
Telephone: 024-23769576 13840269002
Website: www.simchoicechem.com
Company Name: Hunan Zhenyuan Chemical Co. , Ltd.  Gold
Telephone: 18230666727 17575750356
Website: www.chemicalbook.com/ShowSupplierProductsList928225/0_EN.htm
Company Name: Shenyang Shengyuan chemical industry co., ltd  Gold
Telephone: 13190211560
Website: http://www.sysychem.com/
Company Name: Shenyang Delier Biotechnology Co., Ltd.  Gold
Telephone: 15942301471 15942301471
Website:
Company Name: Anhui kuer Bioengineering Co., Ltd  Gold
Telephone: 0551-65171243 13856024262
Website: http://www.kuerhuaxue.com
Company Name: henyang Zhuohua Biotechnology Co., Ltd.  Gold
Telephone: 13940293610 13940293610
Website: www.zhuohuashengwu.com/
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Telephone: 4006356688 18621169109
Website: www.x-labseek.com/
Company Name: future industrial shanghai co., ltd  
Telephone: 400-0066400 13621662912
Website: http://www.jonln.com
Company Name: Alfa Aesar  
Telephone: 400-6106006
Website: http://chemicals.thermofisher.cn
Company Name: TCI (Shanghai) Development Co., Ltd.  
Telephone: 021-67121386
Website: https://www.tcichemicals.com/CN/zh/
Company Name: BeiJing Hwrk Chemicals Limted  
Telephone: 0757-86329057 18934348241
Website: www.hwrkchemical.com/
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Telephone: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Nanjing MeiBo Biological Technology Co., Ltd.  
Telephone: 025-58619198
Website: www.mbbio.com
Company Name: Shandong Xiya Chemical Co., Ltd  
Telephone: 13355009207 13355009207
Website: http://www.xiyashiji.com
Company Name: Syntechem Co.,Ltd  
Telephone:
Website: www.syntechem.com
Tags:143-74-8 Related Product Information
108-95-2 1189-71-5 287-92-3 10049-04-4 591-27-5 90-43-7 141776-32-1 120923-37-7 137-43-9 123-30-8 96-37-7 95-55-6 1074-82-4 124-38-9 14808-60-7 1317-80-2 1758-73-2 100-02-7