| Identification | Back Directory | [Name]
TOTO 1 | [CAS]
143413-84-7 | [Synonyms]
DiTO?-1
Chebi:52298
Toto 1 Iodide
Thiazole Orange Dimer
DiTO-1 (equivalent to TOTO-1) *5 mM DMSO Solution* *CAS 143413-84-7*
1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium
1,1'-(4,4,7,7-Tetramethyl-4,7-diazaundecamethylene)-bis-4-(3-methyl-2,3-dihydro-(benzo-1,3-thiazole)-2-methylidene)-quinolinium tetraiodide
1,1'-{Propane-1,3-diylbis[(dimethylammonio)propane-3,1-diyl]}bis{4-[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]quinolinium} tetraiodide
Quinolinium, 1,1
0
-[1,3-propanediylbis
[(dimethyliminio)-3,1-propanediyl]]bis[4-[(3-methyl-2
(3h)-benzothiazolylidene)methyl]-, Tetraiodide
2,2'-{Propane-1,3-diylbis[(dimethylammonio)propane-3,1-diylquinolin-1-yl-4-ylidenemethylylidene]}bis(3-methyl-1,3-benzothiazol-3-ium) tetraiodide | [Molecular Formula]
C49H58I4N6S2 | [MOL File]
143413-84-7.mol | [Molecular Weight]
1302.77 |
| Chemical Properties | Back Directory | [Melting point ]
>250 ℃ | [solubility ]
Soluble in dimethyl sulfoxide | [form ]
powder | [color ]
Red | [Appearance]
orange solution | [ex/em]
514/533 nm | [ε(extinction coefficient)]
117000 cm−1M−1 | [λmax]
514 nm | [Φ(quantum yield)]
0.34 | [Biological Applications]
Nucleic acid hybridization; nucleic acid amplification assay; DNA fragment sizing; detecting nucleic acids,cells,cystic fibrosis mutations,genes,human papilloma virus (HPV),intact recombinant viruses,oncoprotein | [Major Application]
Marker systems for product
authentication |
| Hazard Information | Back Directory | [Description]
TODi-1 (Thiazole Orange Homodimer, also known as TOTO®-1) is a green fluorescent carbocyanine dimeric dye. TODi-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make TODi-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. TODi-1 is non-cytotoxic and may be used for long-term monitoring of cell viability and dead cell detection in culture. | [Chemical Properties]
ex/em: 514/533 nm
Extinction coefficient (ε): 117000 cm??1M??1
Quantum yield (Φ): 0.34 | [Definition]
ChEBI: ToTo-1 is an organic iodide salt and a cyanine dye. It has a role as a fluorochrome. It contains a ToTo-1(4+). | [Abs/Em Maxima]
514/532 nm |
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| Company Name: |
CHEMICAL LAND21
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| Tel: |
82- 2 -783 - 8063 |
| Website: |
www.chemicalland21.com |
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