| Identification | Back Directory | [Name]
1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride | [CAS]
143692-48-2 | [Synonyms]
GYKI-53655 hydrate
GYKI 53655 hydrochloride
LY300168 hydrochloride hydrate
1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride
5-(4-Aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride | [Molecular Formula]
C19H21ClN4O3 | [MDL Number]
MFCD01941362 | [MOL File]
143692-48-2.mol | [Molecular Weight]
388.848 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
H2O: >10mg/mL | [form ]
powder | [color ]
yellow to orange | [Water Solubility ]
H2O: >10mg/mL | [InChI]
1S/C19H20N4O3.ClH/c1-11-7-13-8-16-17(26-10-25-16)9-15(13)18(22-23(11)19(24)21-2)12-3-5-14(20)6-4-12;/h3-6,8-9,11H,7,10,20H2,1-2H3,(H,21,24);1H | [InChIKey]
ASLCSBBDVWPSQT-UHFFFAOYSA-N | [SMILES]
[Cl-].N1(N=C(c3c(cc4c(c3)OCO4)CC1C)c2ccc(cc2)N)C(=O)NC.[H+] |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P301+P310 | [Hazard Codes ]
T | [Risk Statements ]
25 | [Safety Statements ]
45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
1 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Uses]
GYKI 53655 Hydrochloride is a non-competitive AMPA antagonist,. | [Biological Activity]
GYKI-53655 also inhibits the kainate GluK3 homomeric and GluK2/3 heteromeric receptors. It exhibits anti-ischemicanti-convulsantand acute neuroprotective activity.''GYKI-53655 is an AMPA antagonist and noncompetitive negative allosteric modulator. | [storage]
Desiccate at RT |
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|