| Identification | Back Directory | [Name]
4(3H)-Quinazolinone, 2-butyl-6-(1-methoxy-1-methylethyl)-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- | [CAS]
143945-39-5 | [Synonyms]
CL329167
CL-329167
CL 329167
4(3H)-Quinazolinone, 2-butyl-6-(1-methoxy-1-methylethyl)-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- | [Molecular Formula]
C30H32N6O2 | [MOL File]
143945-39-5.mol | [Molecular Weight]
508.61 |
| Hazard Information | Back Directory | [Description]
CL-329167 is a angiotensin type 1 receptor antagonist potentially for the treatment of hypertension. | [Uses]
CL-329167 (compound 12) is an orally active and competitive angiotensin II receptor antagonist (IC50=6 nM). CL-329167 can be used in the research of hypertension[1]. | [IC 50]
AT2 Receptor: 6 nM (IC50) | [References]
[1] Levin J I, et al. 2, 3, 6-Substituted quinazolinones as angiotensin II receptor antagonists[J]. Bioorganic & Medicinal Chemistry Letters, 1994, 4(9): 1135-1140. |
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