| Identification | Back Directory | [Name]
1H-Pyrrole-1-hexanoic acid, 3,4-dibromo-2,5-dihydro-2,5-dioxo- | [CAS]
1443214-97-8 | [Synonyms]
1H-Pyrrole-1-hexanoic acid, 3,4-dibromo-2,5-dihydro-2,5-dioxo- | [Molecular Formula]
C10H11Br2NO4 | [MOL File]
1443214-97-8.mol | [Molecular Weight]
369.01 |
| Chemical Properties | Back Directory | [Boiling point ]
438.9±45.0 °C(Predicted) | [density ]
1.952±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.74±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC[1]. | [References]
[1] Behrens CR, et al. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs. Mol Pharm. 2015 Nov 2;12(11):3986-98. DOI:10.1021/acs.molpharmaceut.5b00432 |
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