| Identification | Back Directory | [Name]
9-Propenyladenine | [CAS]
1446486-33-4 | [Synonyms]
Tenofovir Impurity B
Tenofovir disoproxil-10
9-(1E)-1-Propen-1-yl-9H-purin-6-amine
Tenofovir Disoproxil Fumarate impurity B
(R)-2-(6-amino-9H-purin-9-yl)propan-1-ol
(E)-6-amino-9-(prop-1-en-1-yl)-9H-purine
Mutagenic Impurity of Tenofovir Disoproxil
USP Tenofovir Disoproxil Related Compound B
9H-?Purin-?6-?amine, 9-?(1E)?-?1-?propen-?1-?yl-
Tenofovir impurity 23/9-Propenyladenine/(E)-9-(prop-1-en-1-yl)-9H-purin-6-amine | [Molecular Formula]
C8H9N5 | [MOL File]
1446486-33-4.mol | [Molecular Weight]
175.19 |
| Chemical Properties | Back Directory | [Melting point ]
143-145 °C | [Boiling point ]
415.6±48.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 29 mg/mL (165.53 mM) | [form ]
Solid | [pka]
4.08±0.10(Predicted) | [color ]
White to off-white | [Major Application]
pharmaceutical (small molecule) |
| Hazard Information | Back Directory | [Uses]
(E)-9-(Prop-1-en-1-yl)-9H-purin-6-amine is a mutagenic impurity in tenofovir disoproxil fumarate and can potentially serve as a key blocking group for the synthesis of 1-?substituted adenines. |
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Shanghai UCHEM Inc.
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http://www.myuchem.com/ |
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