| Hazard Information | Back Directory | [Description]
RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase and cAMP-dependent kinase. | [Uses]
RG 14921 is a compound structurally related to Erbstatin (HY-113549) and has inhibitory activity against EGFR tyrosine kinase and CAMP-dependent kinase activity. RG 14921 inhibits EGF receptor kinase activity as a noncompetitive inhibitor. | [References]
[1] INHIBITION KINETICS AND SELECTIVITY OF THE TYROSINE KINASE INHIBITOR ERBSTATIN AND A PYRIDONE-BASED ANALOGUE |
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