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144924-99-2

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144924-99-2 Structure

144924-99-2 Structure
IdentificationBack Directory
[Name]

N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine
[CAS]

144924-99-2
[Synonyms]

2'-F-N6-Bz-2'-ara-dA
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine
Benzamide, N-[9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-yl]-
N-(9-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
[Molecular Formula]

C17H16FN5O4
[MOL File]

144924-99-2.mol
[Molecular Weight]

373.34
Chemical PropertiesBack Directory
[density ]

1.67±0.1 g/cm3(Predicted)
[pka]

7.87±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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