| Identification | More | [Name]
N-Benzoyl-2'-deoxy-adenosine | [CAS]
4546-72-9 | [Synonyms]
DA-BZ
N6-BENZOYL-2'-DEOXYADENOSINE
N6-BENZOYLDEOXYADENOSINE
N6-BZ-2'-DEOXYADENOSINE
n-benzoyl-2'-deoxy-adenosine
N-BZ-DA
n-benzoyl-2’-deoxy-adenosin
BZ-DEOXYADENOSINE
DA-BZ 99.0%
N(sup 6)benzoyl-2'-deoxyadenosine
N-[9-(2-Deoxy-β-D-ribofuranosyl)-9H-purine-6-yl]benzamide | [EINECS(EC#)]
224-903-6 | [Molecular Formula]
C17H17N5O4 | [MDL Number]
MFCD00009628 | [Molecular Weight]
355.35 | [MOL File]
4546-72-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
120-122C | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
Store at 0°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
7.87±0.43(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in water (slightly), and methanol (20 mg/ml). | [CAS DataBase Reference]
4546-72-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. | [Uses]
Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine. |
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