| Identification | Back Directory | [Name]
m-PEG4-Hydrazide | [CAS]
1449390-68-4 | [Synonyms]
mPEG4-HZ
mPEG3-HZ
m-PEG4-Hydrazide
2,5,8,11-tetraoxatetradecane-14-hydrazide
4,7,10,13-Tetraoxatetradecanoic acid, hydrazide | [Molecular Formula]
C10H22N2O5 | [MDL Number]
MFCD26499475 | [MOL File]
1449390-68-4.mol | [Molecular Weight]
250.29 |
| Chemical Properties | Back Directory | [Boiling point ]
408.1±35.0 °C(Predicted) | [density ]
1.094±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMF, DCM | [pka]
12.82±0.35(Predicted) |
| Hazard Information | Back Directory | [Description]
m-PEG4-hydrazide is a PEG linker containing a hydrazide group. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. | [Uses]
m-PEG4-Hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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ChemPep, Inc.
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