| Identification | More | [Name]
4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid | [CAS]
145069-56-3 | [Synonyms]
4-(2',4'-DIMETHOXYPHENYL)-FMOC-AMINOMETHYL-PHENOXYACETIC ACID
4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID
4-(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC-ACID
4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOL
4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID
4-[(R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID
4-[(R,S)-ALPHA-1-(9H-FLUREN-9-YL)-METHOXY FORMAMIDO]-2,4-DIMETHOXYBENZYLPHENOXYACETIC ACID
FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE
FMOC-AMIDE-LINKER
FMOC-NH-SAL RESIN LINKER
FMOC RINK ACETIC ACID LINKER
FMOC-RINK AMIDE-LINKER
FMOC-RINK LINKER
KNORR LINKER
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE
N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID
P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID
P-((R,S)-ALPHA-[1-(9H-FLOUREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID
P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID
RINK AMIDE LINKER | [EINECS(EC#)]
604-455-1 | [Molecular Formula]
C32H29NO7 | [MDL Number]
MFCD00153509 | [Molecular Weight]
539.58 | [MOL File]
145069-56-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
~180 °C (dec.)
| [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [BRN ]
5841553 | [InChIKey]
UPMGJEMWPQOACJ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1 | [CAS DataBase Reference]
145069-56-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/38:Irritating to eyes and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29242990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Uses]
Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug. | [Application]
Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1]. | [Origin]
Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker. | [reaction suitability]
reagent type: cross-linking reagent | [References]
[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|