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145543-03-9

145543-03-9 Structure

145543-03-9 Structure
IdentificationBack Directory
[Name]

RG 13647
[CAS]

145543-03-9
[Synonyms]

RG 13647
[Molecular Formula]

C30H27N3O5
[MOL File]

145543-03-9.mol
[Molecular Weight]

509.552
Hazard InformationBack Directory
[Description]

RG 13647 is an angiotensin II peptide agonist.
[Uses]

RG 13647 is an AT2-selective ligand. RG 13647 is an analog of PD 123177 (HY-121767). RG 13647 shows weak activity in competing for [125I]angiotensin II binding with an IC50 value of 100 μM. RG 13647 can be used for research of cardiovascular disease[1].
[References]

[1] Jarvis MF, et al. The angiotensin hexapeptide 3-8 fragment potently inhibits [125I]angiotensin II binding to non-AT1 or -AT2 recognition sites in bovine adrenal cortex. Eur J Pharmacol. 1992 Aug 25;219(2):319-22. DOI:10.1016/0014-2999(92)90312-r
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