| Hazard Information | Back Directory | [Description]
BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C. | [Uses]
BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively[1]. | [IC 50]
Aurora B: 7 nM (IC50); Aurora C: 12 nM (IC50); Aurora A: 2153 nM (IC50) | [References]
[1] Yu C, et al. High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines[J]. Nature biotechnology, 2016, 34(4): 419-423. |
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