| Identification | Back Directory | [Name]
Tos-PEG13-Tos | [CAS]
1456708-45-4 | [Synonyms]
Tos-PEG12-Tos
Tos-PEG13-Tos
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol, 1,35-bis(4-methylbenzenesulfonate) | [Molecular Formula]
C38H62O17S2 | [MDL Number]
MFCD28334513 | [MOL File]
1456708-45-4.mol | [Molecular Weight]
855.02 |
| Hazard Information | Back Directory | [Description]
Tos-PEG13-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | [Uses]
Tos-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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