| Identification | Back Directory | [Name]
CALPAIN INHIBITOR XI | [CAS]
145731-49-3 | [Synonyms]
CALPAIN INHIBITOR XI
TZVQRMYLYQNBOA-UHFFFAOYSA-N
Z-L-ABU-CONH(CH2)3-MORPHOLINE
Carbamic acid, [1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl]amino]-2,3-dioxopropyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester (9CI) | [Molecular Formula]
C26H40N4O6 | [MDL Number]
MFCD06411394 | [MOL File]
145731-49-3.mol | [Molecular Weight]
504.62 |
| Chemical Properties | Back Directory | [density ]
1.145±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 5mg/mL | [form ]
Solid | [pka]
11.10±0.46(Predicted) | [color ]
white to off-white | [Sensitive ]
Light Sensitive | [InChIKey]
TZVQRMYLYQNBOA-UHFFFAOYSA-N | [SMILES]
N2(CCOCC2)CCCNC(=O)C(=O)C(NC(=O)C(NC(=O)OCc1ccccc1)CC(C)C)CC |
| Hazard Information | Back Directory | [Uses]
A cell-permeable dipeptidyl -ketoamide that acts as a potent, highly selective, reversible, and active site inhibitor of calpain-1 and -2 | [Biological Activity]
Cell permeable: yes''Primary Target
calpain 1calpain 2''Product does not compete with ATP.''Reversible: yes''Target Ki: 140 nM and 41 nMagainst calpain-1 and -2respectively |
|
|