| Identification | Back Directory | [Name]
Mes-PEG5- THP | [CAS]
145927-73-7 | [Synonyms]
MS-PEG4-THP
Mes-PEG5- THP
Mes-PEG4- THP
CAS_145927-73-7
Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 1-methanesulfonate | [Molecular Formula]
C14H28O8S | [MDL Number]
MFCD29049413 | [MOL File]
145927-73-7.mol | [Molecular Weight]
356.43 |
| Hazard Information | Back Directory | [Uses]
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Biological Activity]
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [IC 50]
PEGs | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 19945035818 |
| Website: |
www.topule.com/ |
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