| Identification | More | [Name]
3-(TRIFLUOROACETYL)INDOLE | [CAS]
14618-45-2 | [Synonyms]
2,2,2-TRIFLUORO-1-(1H-INDOL-3-YL)-1-ETHANONE
3-(TRIFLUOROACETYL)INDOLE
3-(TRIFLUOROACETYL)INDOLE 99% | [Molecular Formula]
C10H6F3NO | [MDL Number]
MFCD00182114 | [Molecular Weight]
213.16 | [MOL File]
14618-45-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
211-214 °C(lit.) | [Boiling point ]
308.6±37.0 °C(Predicted) | [density ]
1.423±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
14.31±0.30(Predicted) | [color ]
White to Almost white | [InChI]
1S/C10H6F3NO/c11-10(12,13)9(15)7-5-14-8-4-2-1-3-6(7)8/h1-5,14H | [InChIKey]
LCMDCXWSHDFQKP-UHFFFAOYSA-N | [SMILES]
FC(F)(F)C(=O)c1c[nH]c2ccccc12 | [CAS DataBase Reference]
14618-45-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
2933992000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
- Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation
- Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid
- Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step
- Reactant for formation of Michael adducts via Baylis-Hillman reaction
- Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides
| [Uses]
Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation. Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid 2 Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step 3 Reactant for formation of Michael adducts via Baylis-Hillman reaction 4 Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides. | [General Description]
3-(Trifluoroacetyl)indole is a heterocyclic trifluoromethyl ketone. One of the methods reported for its synthesis is by the reaction of indole with trifluoroacetic anhydride. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
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https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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