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146196-17-0

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146196-17-0 Structure

146196-17-0 Structure
IdentificationBack Directory
[Name]

N6-Dimethylaminomethylidene-2'-deoxyisoguanosine
[CAS]

146196-17-0
[Synonyms]

N6-Dimethylaminomethylidene-2'-deoxyisoguanosine
2-DEOXY-N-[(DIMETHYLAMINO)METHYLIDENE]-1,2-DIHYDRO-2-OXO-ADENOSINE
[Molecular Formula]

C13H18N6O4
[MDL Number]

MFCD28976113
[MOL File]

146196-17-0.mol
[Molecular Weight]

322.32
Chemical PropertiesBack Directory
[density ]

1.66±0.1 g/cm3(Predicted)
[pka]

8.28±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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